…is used to provide multiple “looks” at the data in clinical trials, providing an opportunity to terminate the trial early when one treatment performs markedly better than the other. The procedure provides an adjustment for the p-values obtained in each look at the data, to ensure that Type I error is controlled.
Week #25 – Fleming multiple testing procedure
- May 30, 2014
- , 9:20 pm
The Fleming procedure (or O´Brien-Fleming multiple testing procedure ) is a simple multiple testing procedure for comparing two treatments when the response to treatment is dichotomous . This procedure...