Epidemiologic Statistics

Epidemiologic Statistics

by David Kleinbaum and Eli Rosenberg

Aim of Course:

This is an introductory epidemiology course that emphasizes the underlying concepts and methods of epidemiology. Topics covered in the course include: study designs (clinical trials, observational studies, case-control studies, and cross-sectional), measures of disease frequency and treatment effect, and controlling for extraneous factors.

This course may be taken individually (one-off) or as part of a certificate program.
Course Program:

WEEK 1:  Epidemiologic Methodology

  • What is epidemiologic research
  • Methodologic issues

WEEK 2:  Study Designs

  • Clinical trial (brief overview)
  • Observational
  • Case-control
  • Cross-sectional

WEEK 3:  Measuring Diseases

  • Morbidity
  • Mortality
  • Incidence
  • Prevalence
  • Risk
  • Rate

WEEK 4:  Measuring Treatment Impact

  • Risk ratio
  • Odds ratio
  • Difference measures
  • Etiologic fraction
  • Number needed to treat
Note: Inference (significance testing and confidence intervals) for metrics like those listed above is covered in related Institute courses such as Biostatistics and Survival Analysis.

WEEK 5: Controlling Extraneous Factors (brief overview)

  • Bias
  • Confounding
  • Stratification
  • Matching


Homework in this course consist of short answer questions to test concepts.

In addition to assigned readings, this course also has supplemental readings available online.

Epidemiologic Statistics

Who Should Take This Course:
Administrators, practicing professionals, researchers, graduate or undergraduate students in the health, medical, and behavioral sciences interested in learning fundamental principles and methods of epidemiologic and public health research. This course is also intended to address increasing demands to provide training to public health professionals and students in developing countries that do not have convenient access to academic training in epidemiology and related public health fields. Specific topics covered in this course will be the purpose of epidemiology, its study designs, measures of disease occurrence and measures of effect, and an overview of control methods for extraneous factors
Course participants should have some background and/or interest in public health, medical research, or research in the behavioral sciences. The mathematics level is basic algebra.  Though not strictly required, if you plan to continue your study of medical statistics beyond this course we recommend taking the introductory course sequence at the Institute before starting this course.  This will allow you to move more readily into further courses for which the introductory sequence is a prerequisite.
Organization of the Course:
Options for Credit and Recognition:
Course Text:

The required course material is ActivEpi courseware, available free online at http://activepi.herokuapp.com . Click "Sign up” in the upper-right, enter the information requested, then confirm your registration via email.  Next, use the "log in” button to enter your email address and password, and click the "ActiveEpi Web” course.  This courseware contains everything you need to complete the course, but, if you wish, you may purchase a printed version of a companion guide here.

Note:  The courseware is also available in CD form (Windows only) from the publisher, Springer, or other retailers such as Amazon.com ("ActivEpi CD”).



November 08, 2019 to December 06, 2019 November 06, 2020 to December 04, 2020

Epidemiologic Statistics


November 08, 2019 to December 06, 2019 November 06, 2020 to December 04, 2020

Course Fee: $589

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We have flexible policies to transfer to another course, or withdraw if necessary (modest fee applies)

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